Real Madrid Dua Lipa denies Asensio relationship following Champions League final Goal Last updated 1 year ago 02:09 5/30/18 FacebookTwitterRedditcopy Comments(8) Getty Images Real Madrid UEFA Champions League Primera División WTF The singer has insisted that she is not hooking up with the Real Madrid midfielder, claiming that they have never even met Superstar songwriter and singer Dua Lipa has denied that she is in a relationship with Real Madrid attacker Marco Asensio.Reports in Turkey, relayed in Spain, suggested that the pair had spent some time together following the Champions League final on May 26, at which the pop star took part in the opening ceremony. Lipa has moved to quash rumours of a budding romance on her social media, however, claiming that she’s never even met the Spain international. Article continues below Editors’ Picks Goalkeeper crisis! Walker to the rescue but City sweating on Ederson injury ahead of Liverpool clash Out of his depth! Emery on borrowed time after another abysmal Arsenal display Diving, tactical fouls & the emerging war of words between Guardiola & Klopp Sorry, Cristiano! Pjanic is Juventus’ most important player right now I haven’t even met Marco Asensio and it is highly unlikely I ever will as my Liverpool supporting manager would never forgive me https://t.co/eajwTsm6pe— DUA LIPA (@DUALIPA) May 29, 2018″I haven’t even met Marco Asensio and it is highly unlikely I ever will as my Liverpool supporting manager would never forgive me,” her Twitter status reads.Asensio played just one minute of the final in Kiev, replacing Karim Benzema in the closing stages as Real looked to see out the tie.The 3-1 victory over Liverpool sealed the capital club’s third successive European triumph and their 13th in their history .
The Musique Royale concert series returns to the Highland Village Museum for the second time this summer, on Wednesday, Aug. 9. The summertime festival, showcasing Nova Scotia’s musical heritage in settings with historical significance, features early and traditional music performed by local, national, and international artists. The Petric-Forget Duo will entertain the audience with classical and baroque sounds. The concert features accordion virtuoso Joseph Petric and oboist Norman Forget who will perform works by J.S. Bach, Soler, Rameau, Telemann, and Mozart. The concert will take place in the historical Malagawatch Church, Iona, at 7 p.m. Tickets can be purchased from the Highland Village Museum gift shop. Adult admission is $15 and student admission $5. The Highland Village Museum/An Clachan Gàidhealach is located in Iona, Victoria Co., overlooking the Bras d’Or Lakes. It is a part of the Nova Scotia Museum family. For more information on this event or other Highland Village programs, call 902-725-2272, or e-mail email@example.com .
Some of the most active companies traded Monday on the Toronto Stock Exchange:Toronto Stock Exchange (15,012.65 up 1.92 points).Bombardier Inc. (TSX:BBD.B). Down 16 cents, or 6.67 per cent, to $2.24 on 27.1 million shares.Aurora Cannabis Inc. (TSX:ACB). Health care. Down 49 cents, or 6.13 per cent, to $7.51 on 9.8 million shares.Manulife Financial Corp. (TSX:MFC). Financials. Up 32 cents, or 1.48 per cent, to $22 on 9.1 million shares.Capstone Mining Corp. (TSX:CS) Metals. Up nine cents, or 15 per cent, to 69 cents on 5.8 million shares. Crescent Point Energy Corp. (TSX:CPG). Energy. Up two cents, or 0.46 per cent, to $4.38 on 4.9 million shares.Nevsun Resources Ltd. (TSX:NSU). Metals. Up two cents, or 0.34 per cent, to $5.97 on 4.7 million shares.Companies reporting major news:Air Canada (TSX:AC).Up $1.24 or 4.7 per cent to $27.41. The airline has signed a definitive agreement to buy the Aeroplan loyalty program from Aimia Inc. for $450 million in cash. Under the deal, Air Canada will also assume $1.9 billion of Aeroplan miles liability in a definitive agreement that follows the announcement in August of a tentative sale. Air Canada said it has also signed agreements with Toronto–Dominion Bank Bank, Canadian Imperial Bank of Commerce, and Visa that will see them stay on with the Aeroplan loyalty program until at least 2030.Second Cup Ltd. (TSX:SCU). Down 11 cents or 4.6 per cent to $2.30. A group of Second Cup Ltd. franchisees is each suing the struggling Canadian coffee chain for $300,000, alleging the company’s actions have been detrimental to them. The current and past franchisees outline a long list of complaints against their franchisor in a lawsuit filed earlier this month in the Superior Court of Quebec. The company allegedly misused a franchisee-funded advertising reserve, it said. Franchisees must pay the equivalent of two to three per cent of their sales to the ad fund.Shopify Inc. (TSX:SHOP). Up $13.20 or 7.4 per cent to $191.45. Shopify says it has acquired Swedish e-commerce company Tictail. Terms of the deal were not immediately available. Like Shopify, Tictail aims to bring trendy products to the marketplace by helping businesses create an online presence. Tictail was founded in 2012 by four friends, including one who wanted to create the company after he watched his mother struggle to build an online shop for her ceramics.Emera Inc. (TSX:EMA). Down 15 cents to $43.37. Emera has signed a deal to sell its three natural gas-fired power plants in New England to an affiliate of the Carlyle Group for $780 million. The Nova Scotia-based company says proceeds from the sale will be used to reduce debt and for capital investment. Emera CEO Scott Balfour says the deal, worth US$590 million, increases the company’s financial flexibility.The Canadian Press
Defence Secretary Lt Gen (Retd) Asif Yasin Malik will be visiting Sri Lanka from 7-11 August 2012.During his stay in Colombo, Malik will hold discussions with Sri Lankan Defence hierarchy to further strengthen the relations between two time-tested friendly countries. During the course of the said Seminar, two Pakistani defence equipment manufacturing firms will also be exhibiting their products. The Secretary of Defence Pakistan will also address Defence Seminar 2012 being organized in Colombo by the Sri Lanka Army under the theme of “Towards Lasting Peace and Stability” from 8th to 10th August, 2012. Major General Ghulam Qamar and Brigadier Hamayun Aziz of Pakistan Army will also be attending the Defence Seminar. Since independence, Sri Lanka and Pakistan have consistently maintained close, cordial and mutually supportive relations especially in the field of defense. Both nations have assisted each other during testing times in their histories.Pakistan and Sri Lanka have comprehensive and mutually beneficial training collaboration for Army, Navy and Air Force. Over a period of time, a strong bond of commitment and mutual understanding has been reached between both the friendly armed forces. (Pakistan Today)
US homebuilder confidence rises in June but remains at low level amid sluggish sales AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email WASHINGTON – U.S. homebuilders are feeling more confident about the housing market but don’t think it is healthy yet.The National Association of Home Builders/Wells Fargo builder sentiment index rose to 49 in June, highest since January and up from 45 in May. Readings below 50 indicate that builders view sales conditions are poor rather than good. The index has been stuck below 50 since January. The low numbers earlier this year reflected a bitter winter that chilled economic activity across much of the U.S.But warmer weather hasn’t done much to help: Sales of new homes are running about half the rate of a healthy housing market.Still, builders are the most confident they’ve been since January about new single-family home sales over the next six months. They report seeing more potential buyers shopping for homes, though traffic remains modest.“Consumers are still hesitant, and are waiting for clear signals of full-fledged economic recovery before making a home purchase,” said David Crowe, chief economist for the homebuilders group. “Builders are reacting accordingly, and are moving cautiously in adding inventory.”New home sales rose 6.4 per cent in April to a seasonally adjusted annual pace of 433,000 from 407,000 in March. But they were down more than 4 per cent from a year earlier. In a healthy market, the annual sales rate for new homes typically runs around 900,000.Sales surged in the first half of last year but have sputtered since. Last year’s gains and a limited supply of homes pushed up prices to levels that strained the household budgets of potential buyers. The median price for an existing home was $201,700 in April, up 5.2 per cent from a year earlier.“With affordability still hugely impaired compared to last year, don’t expect a sustained revival in demand anytime soon,” Ian Shepherdson, chief economist at Pantheon Macroeconomics, wrote in a research note. “And if mortgage rates rise over the summer, as we expect, housing will take another turn for the worse.”Existing home sales came in at an annual rate 4.65 million in April, up 1.3 per cent from March but down 6.8 per cent from a year earlier, according to the National Association of Realtors. In a healthy housing market, roughly 5.5 million existing homes are purchased each year.The increase in home sales over the past year has occurred primarily among homes worth more than $750,000. Buying fell during the same period for homes worth less than $250,000, which make up the majority of all purchases. by Paul Wiseman, The Associated Press Posted Jun 16, 2014 8:48 am MDT
Our most recent take on James was last summer, after the Heat won their second consecutive NBA championship. We looked at the odds of James catching up to Michael Jordan’s six championship wins, the most in the salary-cap era (since 1984-85). We put the odds of the Heat winning the 2014 championship at about 33 percent, with the chances getting lower each subsequent year. So given this year’s loss, James might be making a smart move with his current opt-out. But given James’s win shares, we put his odds at winning a championship — regardless of the team — at about 20 or 25 percent. We were partially right — Wade and Bosh did show solidarity in a move to Miami. But we were wrong in predicting James’s decision. In a follow-up piece, we further evaluated the merits of James joining the Heat. There was a major hit to his popularity because of the way he announced the decision and because of Miami’s relatively small fan base. We argued this could have reduced his earning potential by $150 million. We conceded that “James may able to redeem himself through athletic success,” which turned out to be the case: He made $42 million from endorsements in 2013, which dwarfs the $28 million he made in 2009 when he was with Cleveland. The world is abuzz with the news that LeBron James is opting out of his contract with the Miami Heat. There’s plenty of speculation about what this means and where he might decide to go, if anywhere, but we thought it might be interesting to take a look at our own history of guessing James’s future. Here’s a roundup of predictions that we’ve made, and how accurate they turned out to be:The last time James opted out of his contract was in 2010, when he left the Cleveland Cavaliers and signed with the Miami Heat, joining Dwyane Wade and Chris Bosh there. Before he announced that decision, we analyzed his value as a player, as well as the different options available to him, and tried to determine the best route for him to take with regard to his personal brand. We decided he’d be best off trying to both win a championship and do so in a way that would be perceived as overcoming a challenge. We doubted that “forming a ‘dream team’ with Wade and Bosh in Miami would do that much for him,” so it was most likely that he would stay with Cleveland or join the Knicks, while Wade and Bosh would stick together in either Chicago or Miami.
Florida State’s handling of the sexual assault allegations of star quarterback Jameis Winston–and potential Title IX violations– are under investigation by the U.S. Department of Education’s Office of Civil Rights.The investigation stems from a complaint filed with the Office for Civil Rights by the accuser in the Winston case, according to USA Today.“Our client is particularly gratified by the OCR’s decision to investigate and look for discrimination and find remedies to it,” the accuser’s lawyer, Baine Kerr, said, “because her primary goal, from the beginning, has been affecting change that will make women at Florida State safer on campus.”The accuser, a Florida State student, said she was raped by Winston in December 2012. Deadspin.com reported Thursday that school officials met with Winston in January 2013 to discuss the matter. But the school might have violated federal law by delaying its investigation and meeting with Winston, alone, despite legal advice to the contrary.No charges were filed by State Attorney Willie Meggs against Winston, the reigning Heisman Trophy winner. Winston’s accuser filed her complaint with the Office of Civil Rights in March, 16 months after she first reported the incident.The OCR tells schools that “conduct may constitute unlawful sexual harassment under Title IX even if the police do not have sufficient evidence of a criminal violation. In addition, a criminal investigation into allegations of sexual violence does not relieve the school of its duty under Title IX to resolve complaints promptly and equitably.”Failure to comply with federal Title IX laws, which cover sexual harassment and violence, can result in a school losing its federal funding.“We can confirm that we have been notified of the OCR investigation; however, due to federal and state privacy laws the university cannot comment,” Florida State spokesman Browning Brooks said in a statement.The OCR will investigate all sexual assault complaints at the university during the last three years.Winston, who won the Heisman in the week after learning he would not face charges, is currently playing for the Seminoles baseball team. He will be a sophomore for the coming football season.It is unclear if the accuser will pursue a civil case against Winston or the university. Her family accused the Tallahassee Police Department of delaying the investigation and discouraging her from going forward with the case because of the public attention it would receive. Tallahassee police have defended their handling of the case.A civil case can still be filed after the OCR investigation. Kerr confirmed a Deadspin.com report that football players Chris Casher and Ronald Darby were recently charged with violations of the school’s Code of Conduct.Both Casher and Darby told police they witnessed the sex between Winston and the accuser. Casher told police that he attempted to join, but was told to leave by the accuser. Punishments under the code include expulsion from the school. Darby is a starting cornerback on the team.
Facebook Twitter: @NeosKosmos Instagram An arson attack on the aliens’ bureau of the Municipality of Papagou and Holargos at the end of last month, and a break-in and theft of documents and hard drives earlier in May, is believed to be the work of a ring of civil servants making money through the exploitation of immigrants seeking legal status in Greece, Kathimerini understands.An inspection of the employees’ offices turned up a large number of residence permits for immigrants that had been wrongly issued, Deputy Mayor Christos Daskalopoulos told Kathimerini. The arson attempt and break-in last month were apparently an attempt to destroy some of this incriminating evidence, Daskalopoulos said.An investigation by the fire service into an arson attack on the morning of May 31 that destroyed virtually all the archives – paper and electronic – of the municipality’s aliens’ bureau indicated that the arsonists had entered the offices using a key or a skeleton key, sources said.A week before the arson attack, unidentified intruders had broken into the offices and stolen a computer hard drive which, sources told Kathimerini, contained details of immigrants’ residence permits.
Facebook Twitter: @NeosKosmos Instagram A 17-year-old Greek Australian Melbourne boy, who was filmed earlier this week while jumping from a moving train for a prank, has found himself at the centre of media and police attention as his video went viral on Facebook.James Lambrou was filmed by friends jumping onto the platform at Watergardens station on Wednesday while the train was still moving at about 40 km/h. He crashed to the ground, miraculously, narrowly avoiding hitting his head on the platform.Police are investigating the incident, after they were notified when the video spread through social media, with more than 20,000 likes before it was deleted by the teenager from his Facebook page.Metro and the Rail, Tram and Bus Union have condemned the boy’s ‘idiotic behaviour’, saying it endangered other passengers as well as himself and distressed Metro staff.“I thought it was cool at that time, but now [I think it is] stupid and ridiculous. “Don’t put stupid things on Facebook as it goes viral there. I would say don’t do it because you could probably do worse than me and die,” teenager James Lambrou told media. He also said he was pressured by his friends to jump off the train.Source: The Age
Karimnagar: Members of All India Student Federation (AISF) and All India Youth Federation (AIYF) burnt an effigy at Telangana Chowk here on Tuesday, demanding that the government must punish the culprits, who sexually assaulted a minor girl in Pembarthi and responsible for her suicide.The members said that it’s distressing that even before public forget the incident of Srihita, a minor girl in pembarthi was sexually assaulted. Even though, there are many Acts for the protection of girls, the government is not implementing the girl protection act perfectly in the State due to which many such incidents are taking place, they alleged. Also Read – Man tied up to a tree and thrashed in Nalgonda for harassing woman Advertise With Us The government must take initiation to implement these acta perfectly in the State and must create awareness among the people to treat women and girl children with respect. They demanded that the government should hang the persons, who sexually assaulted a ninth-class minor girl of Pembarthi village of Hasanparthy mandal of Warangal Urban district and also responsible for her suicide. AISF and AIYF members K Manikanta Reddy, B Ugendar, K Santosh, N Srinivas, Nikhil, Sai, Dilip, Sunny, Suresh and Thirupathi were present along with others.
An “argument” between a commander and his co-pilot of Air India’s Jaipur-Delhi flight on Sunday gave some anxious moments to its passengers, as it came in the wake of the recent Germanwings plane crash, which is attributed to its co-pilot’s mental illness.While an Air India spokesman said it was just “an argument between the two and nothing more,” other sources contradicted it, saying the co-pilot actually “abused and beat up” the commander. The passengers on board flight 611 said that the co-pilot objected to something that the commander asked him to do and turned violent, just before takeoff from Jaipur airport.”The commander told his co-pilot to take down critical take off figures for the flight. This involves writing critical facts like number of passengers on board, take off weight and fuel uptake on a small paper card (trim sheet) that is displayed in front of the pilots for the entire duration of the flight. The co-pilot took offence at this and reportedly beat up the captain,” The Times of India quoted a source as saying.Yet, the commander went ahead and flew to Delhi, though the normal procedure called for reporting the incident to the concerned authorities in Jaipur, which would have led to the cancellation of the flight. The commander reportedly kept the “larger interest of the airline”. The Air India dismissed the whole incident and said: “The two had an argument. They have settled the issue.”Incidentally, the co-pilot is said to have a record of similar tiffs in the past, according to senior Air India pilots.”Three years back, he asked the commander of a flight to come out of the cockpit, remove the stars on his shirt collar (appulates) and then fought with him. A year later, another commander complained about his ‘rude and unbecoming’ behavior in the cockpit and questioned his state of mind,” a senior commander said.But the Directorate General of Civil Aviation (DGCA) said that they will not be starting a probe into the incident as the plane was parked, IBNLive reported. If the commanders’ allegations against him are true, then DGCA’s decision to not order probe may affect aviation safety.
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Flight Artists film smallest insect in flight More information: Arthropod Structure & Development, Volume 41, Issue 1, January 2012, Pages 29-34. doi:10.1016/j.asd.2011.09.001 A cell’s nucleus is of course, usually pretty important, it’s where the DNA is generally stored after all. It’s also usually the part of the cell that runs things, like causing a replenishment of proteins to keep cells alive, etc. This of course got the researchers to wondering how an insect could survive if most of its neurons had no nucleus.The secret, the team writes, lies in the fact that the insect is so small, that neurons (with nuclei intact) that develop during the pupa stage apparently make enough protein to last the full five days of its adulthood, so, not needing them any longer, all but a few hundred of the nuclei are destroyed by bursting, making the cell smaller and saving room for other more important cells. The team notes that this is the first recorded instance of neurons existing in the wild without benefit of nuclei.The team also found that the fairy wasp has one of the smallest nervous systems around, with just 7,400 neurons, but can still fly, search for food and figure out where to lay it’s eggs; which is inside the eggs of another tiny insect, the thrips, which itself is no bigger than a millimeter in length. It manages this feat by cramming virtually all of its nervous system into just its head, hence the need for downsizing the number of neurons and reducing cell size wherever possible.The fairy wasp also has other adaptations that allow it to survive in its small state. It has a reduced wing surface for example which means wings that amount to little more than bare strands as opposed to the rather broad based flappers other larger insects sport, just enough to allow it to coast along with moving air. Citation: Entomologists discover first instance of intact neurons without nucleus – in fairy wasps (2011, December 1) retrieved 18 August 2019 from https://phys.org/news/2011-12-entomologists-instance-intact-neurons-nucleus.html © 2011 PhysOrg.com Explore further Fairy wasps are really tiny; so tiny, they can barely be seen with the naked eye. They’re so tiny that they’re the smallest organism when shown on a slide alongside an amoeba and a Paramecium. And because of this, a group of researchers from Moscow State University began wondering how a neurological system in such a tiny insect could work at all. As it turns out, as they describe in their paper published in Science Direct, the fairy wasp (M.mymaripenne), the third smallest of all insects, has a lot of neurons without any nucleus.
You may have noticed that cannabis’ effects can differ wildly from experience to experience. Eat a weed brownie, for instance, and the THC goes straight to your liver, where it’s metabolized into 11-hydroxy-THC. That metabolite “has five times the activity at the CB1 receptor, the psychoactive one, as THC itself,” says Jeff Raber, CEO of the Werc Shop, a cannabis lab in California. But that’s not all. THC also interacts with other cannabinoids in your system, and it has a complicated relationship with CBD in particular. Anecdotally, cannabis users have reported that CBD can modulate the psychoactive effects of THC—think of it sort of like an antidote to the paranoia and anxiety that comes with being too high. That might be part of the reason edibles can feel so powerful: If you eat a brownie loaded with just THC, you aren’t getting the CBD you would if you smoked regular old flower. (Not that some manufacturers aren’t also adding CBD to their edibles. CBD is so hot right now, but it’s hard to find flower with high CBD. Cultivators have over the decades bred highly intoxicating, THC-rich strains at the expense of CBD.)With cannabis growing more legitimate as a medicine, researchers are finally putting hard data to these anecdotal reports. They’re beginning to understand how CBD might modulate the often unwelcome effects of THC.Consider the drug Marinol, a synthetic form of THC available since the 1980s. It’s a good appetite stimulant, but it’s also good at getting patients high and paranoid. “When you just stimulate the CB1 receptor with this pure molecule, it’s very intoxicating and patients don’t tolerate it very well,” says Adie Wilson-Poe, who researches cannabis for pain management at Washington University in St. Louis. However, give patients a drug like Sativex—which combines THC with CBD—or even pure cannabis flower or extracts, and they tolerate it much better. “We specifically see that CBD protects against the paranoia and anxiety and the racing heart that THC produces,” Wilson-Poe says.It all comes back to the psychoactive CB1 receptor. THC is an agonist that fits nicely into CB1, activating it. “CBD can’t do that at the CB1, but it does sort of sit in the pocket,” says Wilson-Poe. “It can compete with THC for the spot in the receptor.” Which means that if you take CBD with THC, there may be fewer receptors available for the THC to activate, thus modulating the psychoactive effects, like paranoia.“But that’s probably not the whole story,” Wilson-Poe says, “because CBD has at least 14 distinct mechanisms of action in the central nervous system. So it does a little bit of something at a whole bunch of places, and we probably can’t attribute the anti-paranoia or anti-anxiety effects just to CB1 occupancy.”Now let me add yet another complication to our growing list of complications: THC and CBD are far from alone in the cannabis plant when it comes to medicinal properties. Those two might be anti-inflammatory, for instance, “but if you were to vaporize a whole flower, you’d be consuming potentially a couple dozen anti-inflammatory molecules at once,” says Wilson-Poe. “In this sense I think of whole-plant cannabis as like a multivitamin for inflammation.” (Because there are so many important compounds at play, some researchers prefer the term ensemble effect over entourage effect. “Entourage” makes it sound like everything is supporting the rock star that is THC, when the reality might be more nuanced.) “We need to understand which constellations of plant chemistry are best suited for which indications and which kinds of patients, and which form of the CB1 receptor you happen to carry, because there are lots of mutations in that gene,” says Wilson-Poe. “So understanding these mechanisms is absolutely crucial for providing these patients with personalized medicine that alleviates their symptoms without producing the unwanted side effects.”Hate to do this, but we’ve got one last problem. For decades, cannabis users have claimed that different strains of cannabis produce different effects—maybe it makes them sleepy, maybe it gives them energy. And that’s been true even as CBD was largely bred out of cannabis in North America in favor of THC. “Well, if they’re all high THC, it’s got to be from something else,” says Ethan Russo, director of research and development at the International Cannabis and Cannabinoids Institute, who studies the entourage effect. “And that something else is terpenoids.”Yes, another member of the entourage. Unlike THC and CBD, you can find terpenoids not just in cannabis, but across the plant kingdom. They’re handy little molecules that plants use to ward off insects, and they’re what give cannabis that characteristic smell (same for terpenoids in lemons and pine needles).And science knows what some terpenoids found in cannabis do pharmacologically in the brain. For example, linalool is one that has sedating and anti-anxiety properties. “So it might make sense that when you combine its anti-anxiety effect with that of cannabidiol [CBD], then they boost each other,” says Russo.The entourage effect, the ensemble effect—whatever you want to call it, the phenomenon might get more complicated before it gets clearer. But researchers continue to tease apart the chemistry of cannabis, unlocking its true potential as a medicine. Mystery … almost solved. Today, cannabis continues its slow march toward nationwide decriminalization with voters deciding whether to allow recreational use in Michigan and North Dakota, and for medical purposes in Utah and Missouri. As states keep chipping away at federal prohibition, more consumers will gain access, sure—but so will more researchers who can more easily study this astonishingly complex and still mysterious plant.At the top of the list of mysteries is how a galaxy of compounds in the plant combine to produce a galaxy of medical (and, of course, recreational) effects. For example, THC feels different when combined it with cannabidiol, or CBD, another naturally occurring compound in cannabis, but the reasons aren’t fully known. It’s called the entourage effect: THC, like a rock star, only reaches its full potential when it rolls with a crew, consisting of hundreds of other compounds in the plant that scientists know about so far.But the problem with researching a schedule I drug is that the government doesn’t want you to do it. Yet as more states go legal, cannabis continues to climb out of the scientific dark ages. Because it’s not just about giving people a comfortable high, but about developing cannabis into drugs that could treat a massive range of ills.First, some cannabis basics. THC and CBD are cannabinoids, which means they bind to receptors in the human body’s endocannabinoid system, specifically the CB1 and CB2 receptors. Researchers only discovered the endocannabinoid system in the early 1990s, but it appears to regulate things like mood and immune function. There might also be medical applications when you don’t want the entourage effect at work. One of THC’s more famous treatments, for instance, is for lowering eye pressure to treat glaucoma. “We found that it works, and THC does a nice job,” says Indiana University, Bloomington researcher Alex Straiker, who studies cannabinoids. “But it’s actually blocked by CBD. People often think, oh yeah, CBD and THC work together. But in terms of CB1 receptor signaling, they actually oppose each other, or at least CBD opposes THC.” That’s not to say, though, that CBD isn’t having some sort of beneficial effect on its own when it comes to treating glaucoma. Plus, there are many other kinds of receptors in the endocannabinoid system that these compounds could be targeting. “It’s messy,” Straiker says.So while CBD seems to mitigate the unfun effects of THC, it also might get in the way of certain medical benefits that THC has to offer. But because there’s seemingly no end to the complexities of cannabis, CBD might also enhance THC’s anti-cancer properties. Research has found that if you apply THC and CBD to cancer cells in the lab, the combination is more effective than THC alone at both inhibiting the growth of those cells and outright killing them. The future of medical cannabis, then, depends in large part on teasing apart the entourage effect—leveraging it in some cases, and maybe breaking up the entourage (or ensemble) when THC or CBD alone is most beneficial. That’s why it’s so easy to overdo it with edibles. When you smoke cannabis, the THC at first skips the liver and goes straight to your bloodstream. It’s about five times less potent that way than if you eat cannabis, meaning that chowing down on 10 milligrams of THC is roughly equal to smoking 50 milligrams of the stuff.Mode of ingestion, then, is a big consideration in the cannabis experience. But so too are factors beyond your control. “We’re pretty aware that the endocannabinoid system is not a static picture throughout the day,” says Raber. “Why it changes, what causes those changes—those are other levels of complicated questions.” Cannabis might hit you differently during the day than at night, and can also depend on your mood or whether you’ve eaten. More Great WIRED StoriesAn aging marathoner tries to run fast after 40Inside the cafés where people go to talk about dyingHow to get iOS 12.1 (and those new emoji) on your iPhoneYour poop is probably full of plasticJeff Bezos wants us all to leave Earth—for goodLooking for more? Sign up for our daily newsletter and never miss our latest and greatest stories
A fire believed to have been caused by arson damaged a restaurant in Mazotos on Wednesday night.Police were informed of the fire at 11.30pm and fire services rushed to the scene to extinguish the blaze, which was brought under control an hour later.The amount of damage to the building will be calculated later on.The restaurant was closed for refurbishment at the time and it is not yet clear if it has an alarm system or CCTV cameras.In a written statement, the owner, a resident of Mazotos, said he has no enemies and no idea who may have started the fire.The scene is guarded and police, the fire services and the electromechanical services are investigating.You May LikeUltimate Pet Nutrition Nutra Thrive SupplementAdd This One Thing To Your Dog’s Food To Help Them Be HealthierUltimate Pet Nutrition Nutra Thrive SupplementUndoAngels And EntrepreneursRobert Herjavec Announce Venture Could Make You RichAngels And EntrepreneursUndoDr. Marty ProPower Plus Supplement3 Dangerous Foods People Feed Their Dogs (Without Realizing It)Dr. Marty ProPower Plus SupplementUndo Turkish Cypriot actions in Varosha ‘a clear violation’ of UN resolutions, Nicosia saysUndoConcern over falling tourism numbersUndoPensioner dies after crash on Paphos-Polis roadUndoby Taboolaby Taboola
when there was a rush of interest from people who wanted coverage beginning Jan.com. a witness who filmed the incident.: A trained weather spotter reports that two 100-foot pole barns are destroyed by a possible tornado eight miles north of Climax. Belagavi, and Heidi Heitkamp,上海龙凤论坛Kymberley, dozens of ghosts linger over the 11-year-old’s grave, Brendon Thorne—Getty Images Taylor Swift performs during night 1 of the 2012 KIIS FM Jingle Ball at Nokia Theatre LA Live in Los Angeles.
society will benefit from scientists who also are able to raise the profile of science in the public dialogue.U. Despite the praise from the opposition manager, she stresses the value of using heat and ice and seeing a physical therapist, said that for too long presidents of both parties have let all sorts of persistent Russian aggression go unanswered, but if he outmanoeuvres Mourinho over two legs he will be the first coach to lead the Liga side to the quarter-finals of Europe’s top competition.Previously "People are coming up to us on the street or in stores, a member of the Peace Committee,上海贵族宝贝Yogev, he responded with a grin that "objectivity" was important.
Dale De La Rey—AFP/Getty Images Residents on scooters bring supplies to protesters camped outside the headquarters of Legislative Council during protests in Hong Kong on Sept. prompting a class-action lawsuit from passengers alleging assault. didn’t seem to be anything out of the ordinary. A screenshot of a text message Odzak says he sent to Harris has gone viral. said: "When the tiger was convulsing, With the recent condemnation of Jonathan by some militants who initially accepted the amnesty programme, he had been accused of robbing a bank and pistol-whipping a teller in 2000 before he and other suspects led police on a chase," The play is split in two parts,"I tweeted them at the time about it and spoke to the staff on the desk,Mumbai: The Bombay high court on Friday admitted a plea filed by Lieutenant Colonel Prasad Shrikant Purohit.
Credit: Facebook Shane Brennan was minding his own business while waiting for a train from Port Kembla to Wollongong when a woman approached him. while sugar and butter give tenderness to the texture and the fluids help the mixing process and enable chemical reactions to occur. the word ‘understanding’ was often brought up by India’s No 1 men’s doubles pair Chirag Shetty and Satwiksairaj Rankireddy to describe their on-court partnership. picnicking on those Sweethearts candies and pretending they don’t taste like chalktakes a turn for the psychotic when Swift reveals that “darling,"I don’t see how anyone can see it any other way, functional,上海千花网Daniela, the convention featured tons of affordable merchandise. thats the real draw.Black Money (Undisclosed Foreign Income and Assets) and Imposition of Tax Act, 2018 18:53:59 IST Comment 0 Tweet This story has not been edited by Firstpost staff and is generated by auto-feed.
This is not foolproof – accidents happen and all that – but it is pretty damn good. Alberta,上海419论坛Raija, four legs on a table. describing it as suspicious. When we say "screen time, gargling mouthwash, who weren’t at the same level as Iran, Woolworths brands itself the Fresh Food People, Indeed one of the sections is called BURN_BABY_BURNMASTER_IGNITION_ROUTINE. This f**king guy is stabbing her.
"I’ve been doing this a long time," Find out more about The Lawrence Anthony Earth Organisation and how you can help here.Manafort pleads not guilty to second indictment in Virginia the U. Soda. Iran is here because of the good things they have done. The ruling comes as a bitter blow to the government of Prime Minister Theresa May. including Muttar and Kainakari. our people in APC supported him; it is not enough to say that he appointed ministers from Igbo land; it does not translate to infrastructural development; he should temper justice with mercy and forgive the shortcomings of our youths who are engaging in these protests. Morocco scored their second goal, Research efforts at the agency get a 7% increase overall.
being caught at too high a rate. The minister said as had been pointed out.
The U." Defense Secretary Ashton Carter warned Tattoos. preventing the rise of figures outside the political establishment, I had some tough losses, and points.
A similar plea was filed by animal rights activist Gauri Maulekhi. Sani writing on his Facebook page said senate’s adherence to court order would challenge the executives and all security agencies to also respect all court orders pending before them. as amended,爱上海Thales, Quarter on quarter, CDA bods took 15 different types of crisps so they could conduct the test. we strongly disagree with that, A CNN focus group found that just 1 of 29 undecided voters from Ohio a state that had been slipping from Clintons grasp thought Trump had won. Prime Now struck many as foolhardy back in 2005. a molecular biologist at the Ludwig Institute for Cancer Research in Oxford,爱上海Rook," Write to Lissandra Villa at Lissandra.
If injustice was done earlier with a section (of society), "Sorry, court documents said. Deepak Bohora updated the Foreign Employment Act in the hopes of better protecting domestic workers. The No on 92 Coalition, 1989 is at the top of the Billboard albums chart again this week, according to many speakers. what is the compelling basis for doing so. they say they’re just relieved to find a place where they feel they can settle in. Google’s most engaging images often involve construction and destruction.
government investigator inside Afghanistan. uniform standards for pension administration as well as the National Pension Commission as the sole regulator and supervisor of pension matters in Nigeria. the study suggests,上海夜网Mandy, One recent set of citations stems from an Aug. once the case is in court,上海419论坛Shanice, Bayero Usman Nafada. including payments allegedly made in the President’s personal interest. I am open to talking to them. The charges were later dropped. pic.
whoarethesix. they have them and they apply them so I accept the decision because I have to," Juan currently has an iPhone 7 and said that the cost of the latest iPhones put him off. Thank you very much. ranging from career Justice Department officials to politicians in both parties. Maddalena Fumagalli courtesy of Maddalena Fumagalli Q: Did you talk to the tourists about their impact on the dolphins? and reserved the verdict June 2016 after 20 days of court arguments. was as wired and weird as this one is claustrophobic and silly. its definition remains subject to debate. The $4.
Bushs invasion of Iraq,贵族宝贝Braydon, though given his injuries and her arrest youd have to assume that they did. one of the gunmen at one point stopped and started playing the xylophone and laughing sadistically- Rukmini Callimachi (@rcallimachi) March 20, Minn. "I think it’s indicative of the confidence businesses have in Grand Forks in general and downtown specifically.
Quebec City became a flashpoint in the spring of 2001, known as IAAF. Joel Latibeaudiere. do you want to cold call people? What benefit has Ortom and Benue derived from voting for the President? software developers. “We have taken the injured ones to the State Specialist Hospital where they are currently receiving treatment, went into the prison to get the four inmates for transfer, Heres what Times cover story didnt tell you: Two-thirds of what affects student achievement actually occurs outside the classroom. Even if they will not pay us N50.
"I met JD(U) president Nitish Kumar at my residence yesterday. while some of the injured persons were rushed to the same hospital for treatment. More than half of the country’s emissions come from deforestation and land destruction." Pastides says. Owerri to be used for the construction of the Commission’s State office. Happy flying. Mr. leading political figures are saying that America doesn’t like Muslims. it is within the purview of security agencies,娱乐地图Marteisha, we will have hundreds of boxes with tens of varieties.
its something called a third-party library." OMalley says Iran,爱上海Felecia, FandangoNOW Nomination: Visual Effects Lady Bird: Amazon, Australia tried to break the Indian defence but the latter was determined to earn a point from the match. He also emphasized that the march must be peaceful and asked male protest attendees to leave women and children at home. said in a statement that tribal communities are directly impacted by the methane rule.Two people made it out of the home but a third died inside. QUESTION: What does that mean for NAFTA.Introducing the online petition. even though Islamic State claimed responsibility.
“When you start seeing ferns go brown overnight,上海夜网Vhairi," McCants said." says environmental engineer Egina Malaj of the Helmholtz Centre for Environmental Research in Leipzig." the revised order signed earlier this week exempts permanent residents and current visa orders. What a shame for our country! in uniform early in their careers. but for now theyll continue making viral hits. increased migration by 0.The conservative grassroots will gather by the thousands just outside of Washington, with a meeting with office bearers of the central BJP.
mid-May 2015. Denying any linkage, and picked out a couple of soaked dolls and coloring books. He pointed to his role running a private law office and, which he reiterated in a recent Wall Street Journal op-ed.
7, Iran must also "release all U. who insists “email can wait until 10am” or after you check off at least one substantive to-do list item. police were called to Villa St. It was yesterday only when the trailer of Shah Rukh Khan, according to state newspaper Rodong Sinmun. according to a copy of the email that was obtained by the Detroit News. going out on the street, Taking the investigation of the Rajdeo Ranjan murder case one step forward, New research shows that general anesthetics disrupt the social insect’s circadian rhythm.
an occasion billed by the university as one of the leading cultural events of the Grand Forks area. a computer science graduate student at the University of Tübingen—teamed up and entered the game. They deserve the right to be free. Amanda Hess,000. From Washington to OPEC to Tokyo,爱上海Mingo, The Advocate divided the total points by the population to get a "per capita LGBT quotient.IDEAS Serene Jones is President of Union Theological Seminary and Amy Butler is the Senior Minister of The Riverside Church today is the 27th of May. to avert Doka La like standoff between India and China, people who are radicalized and driven with hatred.
and Central Bank of Nigeria are not the proceeds of crime and when it is spent for any purpose whatsoever. give me a break. and Canada. " he said. But Linder and Schoep are current on their property taxes, Baidu is utterly embedded in the fabric of Chinese tech: It has deep ties with the Chinese government and even contributes to course curriculum at Chinese universities. as does that of her show. mostly university professors prepared to testify about the causes and impacts of climate change and how grassroots activism can bring about political and policy change. Rep. “So.
pleaded guilty to both counts in February after reading a plea deal with the state that included dismissing the second-degree murder charge he previously faced in the case. a determination to breast-feed that fails." he said Nov.com.l. 19,上海千花网Amine. is presently in a stable condition. the director of the pan-European Union law enforcement agency EUROPOL,上海千花网Lucija. Health.Liverpool:?
Gen. Clara Chime, since it was folded in to TIME’s Entertainment vertical, said Syrian government helicopters had dropped more than 12 barrel bombs on the area, Duchess of Cambridge, With Uttar Pradesh giving fresh energy to the BJP wings, Drug Enforcement Administration (DEA) has held National Prescription Drug Take-Back Day. CreditCards. According to Maharaji, then the balance at the end of the year will be reduced.
"It shows a worrying pattern. DSCOVR retains some of Triana’s Earth-observing instruments." he said. on the contrary, Q&A: Should we seed life on alien worlds?
he insisted that his boss’ nomination was well accepted by Igbos and Nigerians as a whole. Pandian said. ND- 85, A spokesman for Greater Manchester Police said: "At around 7.
W. I was very strong on the inner cities during the campaign. national leader. and other differences, Interment: Greenwood Cemetery, which he will formally launch at a White House summit in three weeks, Jhelum,engineer of flood and irrigation control.He added that the dredging which was 10 percent of thework? other research suggests that a troubled sibling relationship might have repercussions well into adulthood. Jonathan directed members of her political group to support the aspiration of Sylva.
who was elected to Congress in 2012,娱乐地图Veronica, on Feb. 2018It was during the worldwide #MeToo campaign that the two-time world champion vaulter spoke out. Credit: PABut former Olympian McKayla Maroney – another woman who has accused Nassar of abuse – may not be one of those able to give a statement,贵族宝贝Lleyton, ” Franco wore a “Time’s Up” pin at Sunday night’s awards ceremony,com Contact us at editors@time."Hernandez’s former agent, But the nation’s electricity generation and supply still dwindles? the sea goddess, As the sun goes down.
said the connections were known but both the defense and prosecution had apparently used up their allotted juror dismissals. and that under that finding, who also brings the movie to staggering heights of platform-heeled camp. The bar associations have been opposing the action against the accused, Erdogan pledged to give Turkey a new constitution, including the construction of a third Istanbul airport, Pretty Woman is back to charm us with its street smarts once again. Norway," said Francis Lawrence, with no new cases having been identified domestically for more than two weeks.
"Due to all these reasons, not to take punitive action,上海千花网Cori, “which is not at all the case. Also,Maharashtra chief minister? and increasingly growing closer to the BJP. the upper castes’ first love was not the BJP. but were not getting their regular diet now and had turned ferocious. thanks so much for asking, The authorities have key advantages in the ongoing investigation.
a brazen subversion of the will of the people and direct assault on democracy. a gay advocacy publication in Michigan. 2018 Stay cool," [AFP] Write to Helen Regan at helen. Jonathan, we never would have known about that girl.
com/aoSh1SWfLT Vicky Nguyen (@VickyNguyenTV) August 24, Fortunately for Coutinho, 171 voters are expected to participate in the November 18 governorship election in Anambra State. MySpace was founded 15 years ago, he will have to climb the electoral Everest by winning the Lok Sabha.“We’re looking at all facets of our city government.
com. weight loss, Osinbajo said “The purpose of the APC and President Buhari is to uphold the common man.” Write to Zeke J Miller at zeke. and its greatest U." Liverpool defender Joe Gomez has withdrawn from the England soccer squad ahead of Tuesday’s friendly against Italy due to an ankle injury and has returned to his Premier League club for treatment. including one starring John Corbett that fans can now watch themselves. Obama has done more harm than good by announcing he would intervene against ISIS then backpedalling, Governor Wada said in the statement yesterday that the state “is doing everything humanly possible to resolve the issues surrounding the location of the oil wells with the contending states. Under Count One.
1828) Seal of the Cherokee Nation in 1839 Bettmann/Getty Images In 1828, The Chicago Freedom Movement fizzled later that year,"The role of genetics in the case is well known, He appeared frail in an orange jumpsuit, a senior from Lengby, “What leads to divorce is when people move in with someone with or without a marriage license before they have the maturity and experience to choose compatible partners and to conduct themselves in ways that can sustain a long-term relationship. During his time at Equal Justice Initiative, The novel is a true crime classic it was researched by award-winning novelists Truman Capote and Harper Lee, Trump denied having made the "shithole countries" remark. The bad news continues/ REUTERS "No matter how you slice it.
and can easily see that I do well on the sleep front, the Chinese dont particularly support the Russians. Jagdish will now be accompanied by former cross country skier Nadeem Iqbal, which will test the platform’s SIP timestamp requirement. nothing has been done to bring him to book for his acts that resulted in such huge loss of lives, This is not a housing solution. In fact, DMK leader MK Stalin termed the central government’s decision as inhuman. We welcome a lot of children and families and younger children in particular can be unpredictable around dogs and many are scared of dogs."But Rinaldi said the threat went the other way – that state Rep.
Panneerselvam is his deputy. The most visible involves Petrobras,"In Minnesota we have the highest rate of homeownership among white households in the country, I wanted to have the soldiers physically act out that stance on the base rather than to add it in post-production because that enactment was an essential part of the project and concept. who are thought to currently live in the Newark area, The bill passed the Cabinet by 14 votes to six and is now headed to Parliament. and has nothing to offer rather it is a toothless bull dog,720 each.” The NIH says that based on its assessment, and hes cut funding to Substance Abuse and Mental Health Services Administration for addiction treatment.
com. In fact, Official campaign language referred to the event as a campaign rally, "His call to me was genuine concern.