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Glendora Crush set for series GLENDORA – Glendora Blue Crush, a 14-and-younger fastpitch softball team, won a recent tournament in Downey to qualify for the Kids for Baseball Hawaii World Series. AD Quality Auto 360p 720p 1080p Top articles1/5READ MOREGift Box shows no rust in San Antonio Stakes win at Santa AnitaUmpire group has openings The San Gabriel Valley Umpire Association will hold its annual information meeting for prospective umpires on Wednesday at 7 p.m. at Citrus College. No experience is necessary and training is free. For information, call Dennis Miller at (909) 599-9919. Amazons hold player tryouts The Los Angeles Amazons, a member of the Women’s Professional Football League, will conduct player tryouts from 8:30 a.m. to 1 p.m. Jan. 21 at Kelby Park, 815 Barranca Ave. in Covina. WEST COVINA – West Covina Youth Pony Baseball will conduct registration for its upcoming season Saturday, plus Jan. 21-22, from 10 a.m. to 2 p.m. at Walmerado Park, located at the corner of Walnut and Merced avenues. The program is open to youths ages 4 to 14. The league age cut-off has been changed to April 30. Cost is $25. All participants will receive an Amazons T-shirt. Players should wear workout clothes and bring water, a towel and football-type shoes. For more information, call (626) 798-8105 or e-mail firstname.lastname@example.org. Dukes schedule player tryouts The West Covina Dukes baseball team will have tryouts at 10 a.m. on Jan. 28 and at noon on Jan. 29 at Maverick Park, 330 S. Citrus Ave. in West Covina. Players born on or after May 1 are considered 13-year-olds and eligible for this season. The Dukes will have no 14-year-old team this year. For more information, call Duke DeFrates at (626) 480-1411 or visit www.californiadukes.com. Thompson receives job promotion LOS ANGELES – Stephen Thompson, who has been coaching the Cal State Los Angeles men’s basketball team on an interim basis, has been named to the full-time position, the school announced Thursday. Thompson has led the Golden Eagles to a 5-6 overall record and 2-2 CCAA mark as an interim coach following the retirement of former head coach Dave Yanai. “Stephen has done a great job this season,” athletic director Dan Bridges said. “The team is improving daily and I have every confidence he soon will have our men’s basketball program contending for the conference title.” Hacienda LL holds registration HACIENDA HEIGHTS – Hacienda Heights Little League has extended its registration dates. The League will accept sign-ups from 9 a.m. to 1:30 p.m. Saturday and Jan. 21 at Kwis Elementary School, 1925 Kwis Ave. For more information, call Robert Hernandez at (626) 336-5460. Covina Baseball registration set COVINA – Covina Baseball Association will conduct registration for its upcoming season Saturday, plus Jan. 21 and 28 from 9 a.m. to noon at Hollenbeck Park. Fees are $110 for Pony (ages 13-14) and $75 for Colt (15-16). Applications will also be accepted for managers and coaches. In addition, the league is looking for a snack bar chairperson. For more information, call Gil Morales at (626) 966-1617 or Derek Nichols at (626) 960-7210. 160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set!
NEW ERA Tottenham predicted XI to face Brighton with Mourinho expected to make big changes gameday smart causal Every current Premier League club’s best kit from the past decade Arsenal: Leno, Bellerin, Mustafi, Sokratis, Maitland-Niles, Xhaka, Torreira, Ozil, Mkhitaryan, Aubameyang, Lacazette How the Premier League table could change after the Boxing Day fixtures Ramsey could feature How Arsenal could line up in Arteta’s first official game in charge – Ozil return? 2 possible xi highlights 2 Unai Emery has been handed the toughest possible start to life in the Premier League: Pep Guardiola’s Manchester City in front of the Emirates faithful.The new Gunners boss will be hoping Aaron Ramsey is fit after suffering a slight calf injury. The Welshman has returned to training. Tottenham v Brighton LIVE: talkSPORT commentary and team news for Boxing Day opener ALTERED Best clips, calls and talkSPORT moments of 2019, feat Hearn, McCoist and more Sead Kolasinac and Laurent Koscielny are definitely out while Leno, Torreira, Sokratis Papasthathopoulos, Matteo Guendouzi and Stephan Lichtsteiner could all make their competitive debuts.Here is talkSPORT.com’s predicted line-up: impact possible standings How Chelsea could line up against Southampton – what system will Lampard play? LATEST FOOTBALL NEWS Every Championship club’s best signing of the decade, including Taarabt and Dack
There has been widespread shock at the sudden death of popular Letterkenny man Mark Bradley.Mark, 43, passed away suddenly at Letterkenny General Hospital.The popular man, who was from a well-known family from Beechwood, was married to Catherine Harkin. Mark had only taken part in a charity football match in honour of his late brother-in-law Eamonn Harkin who had passed away aged just 41 in April.Mark had been in fine form at the Station House Hotel where he and a host of other Letterkenny people remembered the life and times of Eamonn.Mark was a well-known and popular figure throughout the town and across Donegal and lived in Castleshanaghan with his family.He was a member of the well-known 80s band Ego Minefield. He is pre-deceased by his father Liam and is survived by his wife Catherine and children, mother Josephine and brother Kevin, Declan and Paul.A family friend said the entire community is in shock at Mark’s passing.“It’s just such a devastating blow coming so soon after Eamonn’s recent passing. The family had barely got over that loss.“Now they have to do it all over again with Mark. He was such a lovely lad. He was very talented.“Everyone’s thoughts and prayers are with Catherine and the family and the Bradleys. They’re all juts devastated,” said the friend. EndsSHOCK AT SUDDEN DEATH OF WELL-KNOWN LETTERKENNY MAN was last modified: August 3rd, 2011 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window)Tags:Mark Bradley
Letterkenny General HospitalUPDATED: LETTERKENNY HOSPITAL clinical director Paul O’Connor has confirmed that some nurses are being asked to help staff at Altnagelvin to deal with emergencies there.Where nurses have dual registration which covers the North, they are being asked to help out in Derry, as reported on Donegal Daily yesterday.Other hospital staff are going to work alongside GPs and NowDoc services in the county to help deal with minor ailments normally treated at the Emergency Department. Sean Murphy, the hospital manager, also confirmed Donegal Daily’s story earlier that new equipment arrived last night and that he is hoping to have a standby emergency department ready within the next two weeks.He thanked colleagues in Derry, Sligo and Enniskillen.“We are going to provide staff to NowDoc from Saturday to deal with minor injuries to help relieve pressure on the other hospitals,” said Mr Murphy.He went on: “We are working towards opening the interim Emergency Department (ED) as soon as possible. The mobile diagnostic units for X-ray and CT scans are on site and we have identified a location for them. “The plans for the interim Emergency and Radiology Departments have been agreed with clinical staff and a contractor has been appointed. It will be a couple of weeks before these Departments are fully operational and I can assure you that we are working around the clock to make this happen as soon as possible.“However some of this work is weather dependent. Patient safety and welfare is our paramount concern and we will only start to treat patients when we are absolutely sure that the interim ED can meet those criteria.“From tomorrow morning we will be providing a minor injuries treatment service for patients who come through the NoWDOC service. This is not a walk-in service and we will only be able to treat patients who are referred to the hospital from NoWDOC. This is to ensure that patients who need treatment that we cannot currently provide are not sent to this hospital which would delay the necessary treatment.“Since the ED at the hospital closed we advise that in the case of an emergency, you should call 999 or 112 and ask for the Ambulance Service. For all other situations requiring Emergency Department Services, we advise you contact your GP or GP out of hours service (NoWDOC) in the first instance.“The efforts of all staff in dealing with the aftermath of the flood and the re-establishment of hospital services has been immense. I cannot emphasise enough the professionalism of all staff in the hospital. Two other key players in the recovery effort are Grainne McCann, General Manager of Sligo Regional Hospital and Elaine May, CEO of the Western Health and Social Care Trust. Letterkenny is an extremely busy hospital and it is a credit to Altnagelvin, the South West Acute and Sligo Hospitals that they have coped so well with the additional numbers of patients coming to their Emergency Departments. “The Contingency Management Team remains in place at the hospital to manage the situation. It will be some time before we can confirm when all services will return to their previous levels. In the meantime, patients are being contacted individually to advise on alternative arrangements.“I’d like to once more thank the local community and all of the agencies for their ongoing support and we ask the public for their continued patience and co-operation”, concluded Sean Murphy.HOSPITAL UPDATE: DIRECTOR CONFIRMS DONEGAL DAILY STORY ON NURSES MOVING TO DERRY was last modified: August 2nd, 2013 by John2Share this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window)
This is the tragic toddler killed in an accident at his Letterkenny home yesterday evening.Tragic Joshua Coyle who was killed yesterday. Picture copyright of North West Newspix.Beautiful Joshua Coyle was playing at his home at Crieve Glebe near Bomany when he was struck by a van at around 6.45pm.The 22 month old toddler was rushed to Letterkenny general Hospital but was pronounced dad a short time later. Little Joshua was the son of Alex Coyle and Susanna Mangan.The couple and their other children are being comforted at their home.A full investigation into the incident is being carried out by a Garda Forensic Team who were at the house this morning.Local county councillor Gerry McMonagle said the tragedy has numbed the local community. “Any loss of life in such circumstances in tragic but when it happens to a young child it is even more painful.“As a grandfather myself I was shocked when I heard this news and my heart goes out to the parents and relatives of this little boy,” he said.A post mortem will take place on little Joshua today and his remains are due to be taken back to his parent’s home to be waked. HUGE SADNESS AT PASSING OF TODDLER FOLLOWING TRAGIC ACCIDENT was last modified: September 28th, 2014 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:accidentGardaiJoshua Coyleletterkenny
Police have confirmed that a man aged in his 80’s has died following a road traffic collision.The accident happened on Thursday, March 14 at Crescent Link.Inspector Louise Cummings said: “The collision involving a silver Citroen car and a pedestrian occurred at around 8pm on Thursday evening. “The injured man was taken to hospital but sadly passed away from his from injuries.“The driver of the car was spoken to by officers at the scene and the road was closed for a number of hours following the collision, but has since re-opened.”“Our enquiries are ongoing and I would ask any witnesses to the collision or anyone who may have dash-cam footage to contact officers at Strand Road on 101 quoting reference number 1231 14/03/19.”Tragic news as man dies following road collision in Derry was last modified: March 15th, 2019 by Shaun KeenanShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:Derry
Scientific papers on cell biology continue to uncover amazing things as techniques improve to peer into the workings of these units of life. Here are our Top Ten from the last few weeks:Immunity Tunes: A press release from Johns Hopkins talked about how, unlike other cells, immune cells undergo a “dizzying loop of activity” to generate huge varieties of antibodies through recombination. They liken the regulator of the recombination process to a band leader directing a jam session. (Emphasis added in all instances.)Oxygen Sensor: “Cell’s Power Plants Also Sense Low Oxygen” announced a report from Howard Hughes Medical Institute. In summary, “Researchers have produced the strongest evidence yet that mitochondria – the organelles that generate energy to power the cell – also monitor oxygen concentration in the cell. If oxygen slips below a critical threshold, the mitochondrial ‘sensor’ triggers protective responses to promote survival.” Controlling oxygen levels is important. Both too little and too much can be deadly, not only to the cell, but to the whole organism.Reverse Gear: Nature1 June 9 talked about the myosin monorail trains that ride the microtubule rails. Out of the myosin superfamily of motor proteins, consisting of 18 classes, they were curious how Myosin VI is bidirectional, unlike most of its siblings. They studied its “lever arm,” “power stroke” and “converter” but did not come up with a final model of how it works. “Undoubtedly, this unique myosin family member has yet more surprises to reveal,” they concluded.Transporters: Aussie biologists talked about protein transport into mitochondrial membranes in Current Biology.2 Since there are two membranes, similar to those in chloroplasts (see 01/01/2005 story), there are two squads of transporters to get the cargo in and out. Named TOM and TIM for translocons of the outer and inner membranes, these are “a series of molecular machines” that know how to sort and authenticate objects needing to pass the gates. They envisioned an “entropic spring” mechanism that can help get the cargo passed through “no apparent input of energy.” This type of mechanism is “an emerging theme in biology” that harnesses the disordered motion of molecules to provide binding flexibility and low energy cost to accomplish “a range of functions.” “The TIM23 complex is a smart machine,” they say, describing its ability to grab a piece of cargo, insert it, respond to a stop-transfer signal and reject it, or pass the cargo to the next machine complex.Tissue Triage: Another paper in Current Biology3 discussed how epidermal cells repair damage. The phylogeny of this ability was a puzzle: “Amazingly, while the eyes and hearts of Drosophila and mammals are constructed in entirely different ways and are morphologically quite distinct, their development appears to be under the control of similar master-regulatory transcription factors,” they said. These operations on two vastly different types of organisms cannot be homologous, they suggest; they must be due to convergent evolution. However the repair mechanism arose, it involves signaling and a cascade of coordinated events involving molecular machines. The result? A stitch in time, and wounds that are self-healing. This is another “conserved repair response,” they say, meaning that it is found early in the history of life with little change since.Quality Control: A press release from Yale described a protein that “recognizes misfolded RNAs, creating a RNA quality control system for cells.”Kissing Chromosomes: A news story in Nature4 sheds light on a mystery of gene regulation. We all know chromosomes come in pairs, but how do the genes on each member get expressed together when they are separated by distance? Out of the “many strategies to orchestrate gene activation or repression” in the cell’s bag of tricks, “A three-dimensional examination of gene regulation suggests that portions from different chromosomes ‘communicate’ with each other, and bring related genes together in the nucleus to coordinate their expression.” It’s nice that the spouses are on speaking terms. “Such inter-chromosomal communication has been suspected for some time,” Dimitris Kioussis said, “but this is the first evidence that it actually takes place.” Our understanding of gene regulation has changed from a linear view “to an appreciation that genes are associated with groups of proteins, forming multimolecular complexes,” he said. We’re going to have to see the process not just in snapshots or just a movie: “Is it time to go 4D?” he jests with implicit seriousness. No one knows how the chromosomes are brought together. “How do genes find their appropriate location in the nucleus of a cell, and how are genes that must be expressed herded into active neighbourhoods?” he asks (see “Spaghetti in a Basketball,” 07/28/2004). Whatever the mechanism, “These remarkable findings will puzzle us for some time to come.”Inter-Agency Coordination: Cities have fire departments, police departments, ambulances, highway patrol, disaster response teams and other agencies that sometimes have overlapping duties. Cells do, too. There are multiple repair mechanisms able to respond to different kinds of DNA damage. Scientists writing in Molecular Cell5 discussed what is known about how they coordinate their actions during the emergency repair called TLS (trans-lesion DNA synthesis): “The process requires multiple polymerase switching events during which the high-fidelity DNA polymerase in the replication machinery arrested at the primer terminus is replaced by one or more polymerases that are specialized for TLS. When replicative bypass is fully completed, the primer terminus is once again occupied by high-fidelity polymerases in the replicative machinery.” It sounds like the first-aid squad knows how and when to patch up things enough to get the patient to the surgeon.Texas Tech: Scientists in Texas, publishing in Cell,6 found another multi-talented molecular machine. The rotor part of the V-type ATP synthase (see 02/24/2003 entry) does more than just help acidify vesicles. It also has “an independent function in membrane fusion,” they found. It is essential in the process of exocytosis – what neurons do to transmit their messages. They found that mutant embryos had severe defects in synaptic transmission of nerve signals. (This was found in fruit flies.) By the way, the other form of this rotary motor, the F-type ATP synthase, was called “The World’s Smallest Wind-Up Toy” by Richard Berry in Current Biology.7 Researchers have figured out how to make the motor turn, using magnets. He thinks scientists are on the verge of figuring out how the F0 rotor converts proton flow into torque.Ultimate Spa: Last but not least, scientists at the Salk Institute last month announced a surprising solution to the puzzle of how embryos start their left-right orientation. An “embryonic body wash” operated by cilia sweeps chemical signals across the embryo: “the foundations for the basic left-right body plan are laid by a microscopic ‘pump’ on the outer surface of the embryo’s underside that wafts chemical messengers over to the left side of the body. This sets up a chemical concentration gradient that tells stem cells how and where to develop.” The cilia rotate at a precise 40-degree angle to generate a current over the embryo. The original paper in Cell contains movies of the action. 1Menetrey et al., “The structure of the myosin VI motor reveals the mechanism of directionality reversal,” Nature 435, 779-785 (9 June 2005) | doi: 10.1038/nature03592.2Perry and Lithgow, “Protein Targeting: Entropy, Energetics and Modular Machines,” Current Biology, Vol 15, R423-R425, 7 June 2005.3Stramer and Martin, “Cell Biology: Master Regulators of Sealing and Healing,” Current Biology, Vol 15, R425-R427, 7 June 2005.4Dimitris Kioussis, “Gene regulation: Kissing chromosomes,” Nature 435, 579-580 (2 June 2005) | doi: 10.1038/435579a.5Friedberg et al., “Trading Places: How Do DNA Polymerases Switch during Translesion DNA Synthesis?” Molecular Cell, Volume 18, Issue 5, 27 May 2005, Pages 499-505, doi:10.1016/j.molcel.2005.03.032.6Heisinger et al., “The v-ATPase V0 Subunit a1 Is Required for a Late Step in Synaptic Vesicle Exocytosis in Drosophila,” Cell, Volume 121, Issue 4, 20 May 2005, Pages 607-620, doi:10.1016/j.cell.2005.03.012.7Richard Berry, “ATP Synthesis: The World’s Smallest Wind-Up Toy,” Current Biology, Vol 15, R385-R387, 24 May 2005.Sometimes we just have to rub it in: these are just a few samples from the flood of literature coming out each week in cell biology, biochemistry and genetics (check out another example from 01/27/2003). A little overkill is needed once in awhile, a quadruple jolt of caffeine to make the Darwinists wake up and smell the coffee. Almost none of these papers even mention evolution, and the ones that do only assume it: e.g., Myosin VI “might have evolved to provide unique kinetic characteristics that are potentially important for a reverse-directed motor.” Do they really expect anyone to believe that any more? The papers are filled, on the other hand, with design language: motors, machines, mechanisms, coordinated action, synergy, regulators, signaling, strategies and much more. This illustrates how useless Darwinism is; with apologies to Dobzhansky, nothing in biology makes sense in the light of evolution. Intelligent design, by contrast – whether explicit or implicit – yields profound insights. Let ID be the golden cord to show us the way out of the dark labyrinth where Charlie misled us long ago into the lair of the Minotaur, naturalism.(Visited 9 times, 1 visits today)FacebookTwitterPinterestSave分享0
Despite the Odisha government’s order to waive all academic fees for physically challenged students, several government and government-aided higher secondary schools are collecting admission fee from them.As per an order of the Department of School and Mass Education of Odisha dated May 25, 2018, ‘all academic fees, except mess charges, will be waived in respect of students with disabilities of 40% or more’. But due to ignorance of authorities of some higher secondary schools, physically challenged students are being pressed to pay up admission fee during admission to +2 courses.Immediate declaration Retired principal of Red Cross School for the Blind in Berhampur, Nabin Chandra Satapathy, has brought this to the notice of the State Commissioner for Persons with Disbilities, Odisha. Mr. Satapathy, who is actively involved in issues related to bind students, demanded that the government make some immediate declaration so that higher secondary schools stop collecting admission fee from blind students during admissions.In his representation, Mr. Satapathy has cited example of three visually impaired students who have passed the tenth board examination from Red Cross School for the Blind, Berhampur, and have got admitted in different higher secondary schools of the State. Receipts of these students clearly state that admission fee was collected from them.This error has happened in top higher secondary institutions of the State like Ravenshaw Higher Secondary School, Cuttack, and Khallikote Higher Secondary School, Berhampur. “Dutikrushna Jena had to pay over ₹4000 to get admitted in +2 first year of arts course in Muniguda Junior College of Rayagada district. Similarly S.Nahak had to pay ₹961 for admission to higher secondary arts course of Ravenshaw Higher Secondary School, Cuttack. Prabhakar Sethi paid ₹1,062 for +2 arts admission in Khallikote Higher Secondary School, Berhampur,” said Mr. Satapathy.
The Congress in Goa on Monday thanked former Chief Minister Laxmikant Parsekar for his “boldness” in exposing his own party’s Chief Minister Manohar Parrikar, in connection with a complaint before the Lokayukta on illegalities in second renewal of 88 leases in the mining industry. Speaking to the press here, A. Chellakumar, AICC general secretary in-charge of Goa further said that an affidavit filed by Mr. Parsekar before the Goa Lokayukta, which is probing an illegal mining scam, also exposes the lies peddled by the BJP when it was in opposition and had blamed Congress leaders of committing a ₹35,000 crore illegal mining scam.“Mr. Parrikar sitting in opposition had gone on a padayatra and undertook many agitations. He had told so many lies. He went to any extent to brand Congress as corrupt,” Mr. Chellakumar said and added that Mr. Parsekar’s affidavit now exposes those behind the mining scam.Mr. Parsekar had succeeded Mr. Parrikar as CM, after the latter joined the Union Cabinet as Defence Minister in 2014. Mr. Parsekar was defeated in the 2017 Assembly elections, and Mr. Parrikar again took charge as Chief Minister after resigning as Defence Minister. In his affidavit filed before the Goa Lokayukta, Mr. Parsekar, who is made one of the respondents in illegal mining scam case by NGO Goa Foundation, has claimed that “certain individuals”, who were involved in the process for granting the renewals were “left out” by the complainant. He further said that he was being targeted selectively at the behest of vested interests as he was no more holding any position of power .Responding to this affidavit, the petitioner Claude Alvares, Director, Goa Foundation had declared on Saturday that Mr. Parrikar, who was also Chief Minister at the time the first six mining leases were granted for second renewals, will be made party to the case before the Lokayukta. He said that initially he had left out Mr. Parrikar as he was unwell. The Goa Foundation complaint before the Lokayukta has called it a ₹1.44 lakh crore second renewal scam.